New Class of Orthopoxvirus Antiviral Drugs That Block Viral Maturation
نویسندگان
چکیده
منابع مشابه
New class of orthopoxvirus antiviral drugs that block viral maturation.
By using a homology-based bioinformatics approach, a structural model of the vaccinia virus (VV) I7L proteinase was developed. A unique chemical library of approximately 51,000 compounds was computationally queried to identify potential active site inhibitors. The resulting biased subset of compounds was assayed for both toxicity and the ability to inhibit the growth of VV in tissue culture cel...
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We thank all the respondents to the survey and the nurses at the Leicestershire Hospice for their interest and willing participation, Dr Carol Jagger for statistical help, and Miss K Jeffery for preparing the typescript. I St Christopher"s Hospice Iniformation Service. 1988 Direcion, of liospiCe serz.ices. Svdcnliaini: St (hristopher's Hospice, 1988. 2 Hill F, Oliver C. Hospice-thc cost of in-p...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2004
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.78.22.12147-12156.2004